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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX1 All Species: 23.64
Human Site: S1100 Identified Species: 43.33
UniProt: P39880 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P39880 NP_853530.2 1505 164273 S1100 S D P P A S D S Q P T T P L P
Chimpanzee Pan troglodytes XP_527845 1515 165612 S1111 S D P P A S D S Q P T T P L P
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 S1377 S D P P A S D S Q P A T P L P
Dog Lupus familis XP_546939 1411 154543 S1041 S D P P A S D S Q P A T P L P
Cat Felis silvestris
Mouse Mus musculus P53564 1515 165577 S1095 S D P P A S D S Q P T T P L P
Rat Rattus norvegicus P53565 862 92341 T499 G E T I L G L T Q G S V S D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 Q1091 T Q A P A G I Q E I V A M S P
Chicken Gallus gallus XP_425393 1673 183755 S1239 S E P P A S E S Q S T T P L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 V981 Q P L E P H G V K S S V M I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 H1591 K P M L M P V H G T N A M R S
Honey Bee Apis mellifera XP_623857 1936 209316 M1477 L H S P H H Q M A P S P L R G
Nematode Worm Caenorhab. elegans Q9BL02 1273 143507 S910 F M D D V E A S E E N D E K Q
Sea Urchin Strong. purpuratus XP_780858 1460 163719 K1068 S K P K M W L K L S M K G R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 83.1 56.2 N.A. 88.8 47.1 N.A. 44.3 77.4 N.A. 40.9 N.A. 23.3 23.7 22.3 29.1
Protein Similarity: 100 98.6 83.4 64.5 N.A. 91.8 50 N.A. 60 81.7 N.A. 55.4 N.A. 37.4 41 41 46.6
P-Site Identity: 100 100 93.3 93.3 N.A. 100 6.6 N.A. 20 80 N.A. 6.6 N.A. 0 13.3 6.6 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 100 26.6 N.A. 33.3 93.3 N.A. 26.6 N.A. 0 20 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 54 0 8 0 8 0 16 16 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 39 8 8 0 0 39 0 0 0 0 8 0 8 0 % D
% Glu: 0 16 0 8 0 8 8 0 16 8 0 0 8 0 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 16 8 0 8 8 0 0 8 0 8 % G
% His: 0 8 0 0 8 16 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 8 0 0 0 8 0 % I
% Lys: 8 8 0 8 0 0 0 8 8 0 0 8 0 8 0 % K
% Leu: 8 0 8 8 8 0 16 0 8 0 0 0 8 47 8 % L
% Met: 0 8 8 0 16 0 0 8 0 0 8 0 24 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % N
% Pro: 0 16 54 62 8 8 0 0 0 47 0 8 47 0 62 % P
% Gln: 8 8 0 0 0 0 8 8 54 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 24 0 % R
% Ser: 54 0 8 0 0 47 0 54 0 24 24 0 8 8 8 % S
% Thr: 8 0 8 0 0 0 0 8 0 8 31 47 0 0 0 % T
% Val: 0 0 0 0 8 0 8 8 0 0 8 16 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _